Gout: A Guide to Causes, Symptoms and Treatment 

Gout is a common, painful type of arthritis caused by a build-up of uric acid crystals in the joints. Attacks often begin suddenly, causing intense pain, swelling and redness, most frequently in the big toe. Treatment focuses on relieving pain during a flare-up and taking daily medication to lower uric acid levels and prevent future attacks. Waking up in the middle of the night with a big toe that is red, swollen, and fiercely painful is an alarming experience. This sudden distress is a classic sign of gout, a very common and treatable form of inflammatory arthritis. Understanding the condition is the first step towards taking control, managing painful attacks, and preventing them from returning.

 

What is gout and how does it feel?

Gout is a type of arthritis caused by high levels of a substance called uric acid (or urate) in your blood. The body produces uric acid when it breaks down purines, which are chemicals found naturally in human cells and certain foods.

Uric acid and crystals

Normally, uric acid dissolves in the blood and passes out of the body through your kidneys. When there is too much uric acid, it can form tiny, sharp crystals in and around your joints. The immune system reacts to these crystals, triggering an intense inflammatory response. According to the NHS, gout usually affects the big toe, but it can also occur in the feet, ankles, knees, hands, wrists, elbows or fingers.

Symptoms of a gout flare

A gout attack, or flare-up, causes sudden and severe joint pain. Patients often describe the pain as throbbing or crushing. The affected joint becomes extremely tender, to the point where even the weight of a light bedsheet resting on it can feel unbearable. The skin over the joint typically looks shiny and red, and the area feels hot and swollen. Attacks frequently start at night and develop rapidly over a few hours. A severe flare can last for five to seven days before improving, although the joint may feel stiff and uncomfortable for several weeks afterwards.

Common gout myths and facts

A persistent myth is that gout is a disease caused entirely by overeating and heavy drinking. In reality, gout is a complex medical condition. While diet plays a role, genetics, kidney function, and other health issues are far more significant factors in deciding who develops the condition. Another common misconception is that you must completely eliminate all red meat and alcohol to manage gout. Total abstinence is rarely necessary; moderation and a balanced approach are much more effective. Gout is a legitimate form of arthritis, not a reflection of your lifestyle choices.

Gout symptoms and diagnosis

Gout symptoms are distinct and progress quickly, allowing a GP to diagnose the condition through a physical exam and blood tests.

Signs of a gout attack

You are likely to experience:

  • Intense, sudden joint pain.
  • Noticeable swelling and inflammation.
  • Red, tight, and shiny skin over the joint.
  • The joint feeling very hot to the touch.
  • Lingering discomfort and stiffness after the most severe pain settles.

If left untreated for years, chronic gout can cause an inflammatory reaction that leads to tophi, as noted by NHS inform. These are small, chalky lumps of uric acid crystals that form under the skin, often on the ears, fingers, or elbows.

Close-up of hands massaging a swollen, bruised ankle

When to see a GP

You should speak to a GP if you experience the symptoms of a gout attack for the first time. Getting a firm diagnosis is important to rule out other serious conditions, such as a joint infection. Our online GPs regularly speak to patients experiencing painful joint flare-ups and can guide you on the right treatment plan.

When to get urgent help

  • Call 999 or go to A&E if: you have joint pain along with a very high temperature, you feel hot and shivery, or the skin around the joint has changed colour. These can be signs of sepsis or a severe joint infection (septic arthritis).

  • See a GP urgently if: your joint pain is severe, getting worse quickly, or you feel generally unwell with the pain.

How a GP diagnoses gout

During an appointment, a GP will ask about your symptoms, diet, lifestyle, and family medical history. They will also carry out or arrange a physical examination of the affected joint. To confirm the diagnosis, they will usually request a blood test to measure the level of uric acid in your blood. Because uric acid levels can sometimes drop and appear normal during an acute attack, you may need to repeat the blood test four to six weeks later.

If the diagnosis remains uncertain or unconfirmed, then a referral to secondary care might be appropriate for joint aspiration, where a specialist uses a thin needle to draw a small amount of fluid from the joint to check for crystals under a microscope. Scans, such as an ultrasound or a CT scan, may also be used to look for crystal deposits or signs of joint damage.

What causes gout and who is at risk?

Gout is caused by a build-up of uric acid in the blood, with risk factors including being male, getting older, genetics, obesity, and certain medications.

Main risk factors

Key risk factors include:

  • Being male.
  • Getting older.
  • Genetics, particularly having a close family member with gout.
  • Being overweight or living with obesity.
  • Taking certain medications, such as diuretics (water tablets) prescribed for high blood pressure.

Linked health conditions

Gout is closely linked to several other health conditions, primarily because of how the body handles uric acid.

  • Kidney disease: The kidneys are responsible for filtering uric acid out of the blood. If you have poor kidney function, your body struggles to excrete uric acid effectively, causing it to build up in your system.
  • High blood pressure: Having high blood pressure can reduce blood flow to the kidneys, making them less efficient at removing waste. Some medications used to treat high blood pressure can also raise uric acid levels.
  • Diabetes and metabolic syndrome: Insulin resistance, a key feature of type 2 diabetes and metabolic syndrome, can impair the kidneys' ability to remove urate, increasing the risk of a gout attack.

Common gout triggers

If you already have gout, certain triggers can cause a sudden attack. NHS 111 Wales highlights that medical treatment and lifestyle awareness can help prevent these triggers. Common triggers include:

  • Dehydration.
  • Drinking too much alcohol, especially beer, or sugary drinks.
  • A sudden illness that causes a fever.
  • An injury or recent surgery on a joint.
  • Eating a very large meal rich in purines, such as red meat, offal, or shellfish.

How to manage a gout flare-up

To manage a gout flare-up effectively, you should rest the joint, apply ice, stay hydrated, and take prescribed anti-inflammatory medication as soon as symptoms begin.

Immediate steps for gout relief

  1. Take medication: If a doctor has prescribed painkillers or anti-inflammatory medicine for a flare, take them as soon as possible. Early treatment is much more effective.
  2. Rest and elevate: Keep the affected joint rested and raised on a cushion to help bring down the swelling.
  3. Apply ice: Wrap an ice pack or a bag of frozen peas in a tea towel and hold it against the joint for up to 20 minutes at a time. This cools the area and provides pain relief.
  4. Stay hydrated: Drink plenty of water. This supports your kidneys in flushing excess uric acid out of your body. Avoid alcohol and sugary drinks completely during an attack.

Medicines for immediate gout relief

Doctors typically recommend one of three types of medication to treat the immediate symptoms of a gout attack:

Medication type

How it works

When it is used

Non-steroidal anti-inflammatory drugs (NSAIDs)

Medicines like ibuprofen or naproxen quickly reduce pain and inflammation in the joint.

Recommended as a first-line option to treat immediate symptoms.

Colchicine

A prescription medicine to relieve gout attacks, as noted by the NHS.

Recommended as a first-line option to treat immediate symptoms.

Corticosteroids

Powerful anti-inflammatories, such as prednisolone, taken as tablets or injections.

Used for severe attacks or if NSAIDs and colchicine are not suitable for you.

Long-term treatment to prevent gout attacks

Long-term treatment for gout focuses on daily urate-lowering therapy (ULT) to consistently reduce blood uric acid levels and prevent future attacks.

Urate-lowering therapy (ULT)

Lowering your uric acid dissolves existing crystals and stops new ones from forming. This approach is called urate-lowering therapy (ULT). NICE recommends aiming for a target serum urate level below 360 micromol/litre (6 mg/dl). A GP will usually suggest starting ULT if you have had two or more gout attacks in a year, or if you have visible tophi or joint damage.

Common gout prevention medicines

There are two main medications prescribed in the UK for urate-lowering therapy.

Feature

Allopurinol

Febuxostat

How it works

Reduces the amount of uric acid your body produces.

Reduces uric acid production in a similar way to allopurinol.

When to start

Usually started a few weeks after a gout flare has completely settled.

Used if allopurinol is not suitable, or if allopurinol causes side effects.

Key considerations

The starting dose is low and gradually increased until your target uric acid level is met.

Regular blood tests are needed to check your liver function and uric acid levels.

Common side effects

Mild skin rash.

Headache, nausea, or a mild skin rash.

Starting a new gout medication

It is very common to experience a temporary increase in gout attacks during the first few months of starting urate-lowering therapy. This happens because the medication is doing its job: as blood uric acid levels drop, existing crystals in the joints begin to dissolve and break apart, which can trigger inflammation.

To prevent this, a GP will often prescribe a low daily dose of an anti-inflammatory, such as colchicine, for the first three to six months alongside your new preventative medicine. Urate-lowering therapy is a long-term, often lifelong commitment. It is vital that you continue taking it every day, even when you feel well, and do not stop without speaking to a doctor. Our virtual GPs can help review your medication and adjust your dosage safely through an online appointment.

Diet and lifestyle changes for managing gout

Managing gout requires sustainable lifestyle changes, including maintaining a healthy weight, eating a balanced diet, and drinking plenty of water to reduce uric acid levels.

pexels-matthew-baxter-1366354232-33975355

Gout-friendly diet

Maintaining a healthy weight is one of the most effective steps you can take, as it eases pressure on your joints and improves how your body processes urate. NICE highlights the importance of discussing lifestyle choices like diet and weight management during your consultations. Focus on a balanced diet rich in vegetables, whole grains, and fruit. Some studies suggest that cherries and low-fat dairy products may be particularly beneficial for people with gout.

pexels-mikhail-nilov-6740535 (2)

High-purine foods

Foods high in purines can increase uric acid, but you do not need to cut them out entirely. Instead, aim to eat them in moderation. High-purine foods include:

  • Red meat, such as beef and lamb.
  • Offal, including liver and kidneys.
  • Certain types of seafood, like sardines, mussels, and scallops.
  • Yeast extracts.

While a sensible diet helps, it is important to remember that medication is the primary treatment for preventing attacks. Diet is a supportive measure, not a substitute for clinical care.

pexels-burst-374862

Hydration and drinks to avoid

Drinking plenty of water, around two litres a day, is crucial. Good hydration helps your kidneys function well and supports them in filtering uric acid out of your blood. You should strictly limit your intake of beer and spirits, as these are strong triggers for gout. Sugary drinks and snacks, particularly those high in fructose, should also be avoided where possible.

Getting treatment and support for gout

Getting treatment and support for gout involves managing acute flare-ups with painkillers and taking long-term preventative medication to lower uric acid levels.

While eating well and staying hydrated play an important role, urate-lowering therapy remains the most effective way to protect your joints and prevent future attacks. With the right care plan, you can live a full, active life free from the distress of painful flares.

The most important step you can take is to speak to a GP to confirm your diagnosis and create a personalised treatment strategy. Booking an online GP appointment gives you a simple way to discuss your symptoms, review your triggers, and arrange any necessary prescriptions to keep your gout under control.

Frequently asked questions

Gout is indeed a lifelong condition. However, as one NHS (local service) explains, while there is no cure, there are treatments available that can help relieve symptoms and reduce the likelihood of further attacks. With daily urate-lowering medication and healthy lifestyle adjustments, most people can prevent attacks entirely.

You can take paracetamol for gout pain, but it might only offer very mild pain relief because it does not treat the severe inflammation that causes gout pain. Anti-inflammatory painkillers like ibuprofen or naproxen are significantly more effective during an attack to reduce both the pain and the swelling.

The difference between gout and arthritis is that arthritis is a broad medical term used to describe over 100 different conditions that cause pain, swelling, and stiffness in a joint. Gout is one specific type of inflammatory arthritis, which is caused directly by a build-up of uric acid crystals in the joints.

It takes allopurinol a few days to begin working to lower your blood uric acid levels. However, it can take several months, or even up to a year, for the medication to fully dissolve the existing uric acid crystals in your joints and significantly reduce the frequency of gout flare-ups.

You should start taking preventative gout medication, such as allopurinol, when a doctor recommends it, which is generally after you have experienced two or more gout attacks within a 12-month period. Preventative treatment is also commonly started if you have complications like visible tophi or evidence of permanent joint damage.

See a UK GP today

Skip the wait — book an online appointment and get expert advice from a UK-registered clinician in as little as 2 hours. 

Related Topics